ANTIGENICITY OF GELATIN

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Antigenicity of Gelatin

The effects of physical and enzymatic treatments of gelatin on the gelatin-antigelatin reaction have been presented. The data obtained indicate that the gelatin-antigelatin reaction is indeed a specific one. It appears that a definite limiting molecular size and specific molecular pattern of this molecular unit are necessary for reaction with antibody.

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I. Antigenicity of Oxypolygelatin and Gelatin in Man

It has been demonstrated that there are normally occurring antibodies to gelatin in human sera. Immunization with gelatin can in many cases increase the antibody level. The presence of these antibodies does not result in cutaneous reactions of the wheal and erythema type after injection of antigen. Many of the properties of the gelatin-antigelatin reaction and the precipitates formed are those ...

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Ii. Antigenicity of Gelatin in Rabbits and Other Species

Normally occurring antibodies to gelatin have been demonstrated in sera from many species. Immunization of rabbits with gelatin has been successful when adjuvant techniques were employed.

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Antigenicity of Mucins

ined for ability to produce mucins with human blood group A, B, and H activity. Blood group activity of the mucins was compared to antigenic activity of red blood cells in individual rats and the enzymatic basis for differences was investigated. Red cells in all the rats examined contained human blood group A and B antigens. All rats synthesized intestinal mucins having B and H antigenic activi...

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Antigenicity of bdellovibrios.

Antigenic relationships between 12 locally isolated bdellovibrios and 3 established reference strains (109D, 6-5-S, and UKi2) were investigated. Antigenicity of the strains was examined by use of the micro-complement fixation test, the serum and complement bactericidal test, and the immunodiffusion test. Antisera were prepared against one of the local strains (MS7) and against one of the establ...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1958

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.107.1.125